Simvastatin may effectively attenuate DN progression through down - regulating the expression of TGF - ? ? via p 38 MAPK.
斯伐他汀可能通過抑制p38MAPK磷酸化而減少TGF - β的蛋白表達.
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Objective To investigate the influences of simvastatin on carotid artery Intima - media thickness ( IMT ) and carotid atherosclerotic plaque.
目的探討辛伐他汀對頸動脈內(nèi)膜-中膜厚度及頸動脈粥樣硬化斑塊的影響.
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Both simvastatin and CDPC can relieve the damages of the brain in rats HIBD.
辛伐他汀和胞二磷膽堿可減輕新生大鼠HIBD后腦組織損害.
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Methods: Simvastatin was synthesized from lovastatin via acetylization, methylation, hydrolytic decomposition and cyclization reactions.
方法: 以洛伐他汀為原料,通過酰化 、 甲基化 、 水解、環(huán)合等反應(yīng)合成了辛伐他汀.
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OBJECTIVE To prepare sustained - release dropping pills of Simvastatin and optimize its preparation technology.
目的制備辛伐他汀緩釋滴丸并優(yōu)化其制備工藝.
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CONCLUSION Early Simvastatin treatment effectively improves the cardiac function in ACS patients in a dose - dependent manner.
結(jié)論早期大劑量辛伐他汀干預(yù)能安全有效地改善ACS患者的心功能,降低心律失常的發(fā)生率,且呈劑量依賴性.
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