The inhibition effect of BACE siRNA on BACE expression was investigated by fluoroscopy and immunohistochemistry method.
制備穩(wěn)定高表達(dá)BACE基因的神經(jīng)母細(xì)胞瘤SK-N-SH 細(xì)胞株,用熒光顯微鏡和免疫組織化學(xué)的方法觀察siRNA對(duì)BACE表達(dá)的影響.
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B - RAF - siRNA inhibited BGC 823 cell prolifera - tion and induced apoptosis ( P & lt; 0.01 ).
促進(jìn)胃癌BGC823細(xì)胞的凋亡 ( P & lt; 0.01 ).
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We also explored the effect of ephrinB siRNA for neuropathic pain.
同時(shí)探討ephrinBsiRNA對(duì)于神經(jīng)性疼痛的作用.
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Objective To construct eukaryotic expression vector of siRNA specific for ? ? - site APP cleaving enzyme ( BACE ).
目的構(gòu)建β淀粉樣前體蛋白裂解酶 ( BACE ) 特異性小干擾RNA真核表達(dá)載體.
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Conclusion: siRNA of hTERT can inhibit the expression of human telomerase and proliferation of ALVA - 41 cells.
結(jié)論: 應(yīng)用RNA干擾技術(shù)可阻止hTERT基因的表達(dá),抑制腫瘤細(xì)胞的增殖.
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The vector, PCH and pGH, will be used to study prevention of virus in fection.
研究結(jié)果表明構(gòu)建的載體有效表達(dá)了siRNA, 這些載體可以用于與siRNA相關(guān)抗病毒治療性試驗(yàn)研究.
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Results: We observed through the FAM that the transfected efficiency was about 65 - 80 %.
結(jié)果: 利用FAM熒光標(biāo)記觀察到siRNA轉(zhuǎn)染效率可達(dá)65~80%.
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