Siren Phillips has lived her life thinking she's an ordinary girl, in an ordinary town. On the eve of her twelfth birthday, however, she learns that she is far from ordinary. Destined to turn into a Mermaid at the age of twelve, Siren must struggle with her new reality, saying good-bye to her mother and friends, while she transitions into the water. To make matters worse, a group of hunters are trying to catch her. She soon becomes friends with Adam Wilts, a new boy at school, who she turns to for help. He agrees to help her, but finds himself caught in the middle, when it's his own father who is after Siren. When Siren's mother is taken, the town must rally behind her, and help her make a peaceful transition into the water, before the hunters can find out where she is.
Upon hearing of his mentor's impending death, haggard musician Kino Warren begins a journey on foot across country, and through a place not of this world referred to as "the territory". Kino believes wholeheartedly that the mentor cannot die until he arrives. On his journey, Kino is unaware several people are on his tail - varyingly malicious and politically involved - in search of the only-known recording of the greatest piece of music ever made, a piece supposedly capable of taking away all pain within the listener - created by his mentor, and in his possession, completely unbeknownst to him.