桑福德（約翰·庫噓 John Cusack 飾）是一名精神病醫(yī)耆童，在治愈他人病的同時，桑福德自的家庭卻傷痕累累。子本杰（伊萬·伯?踢 Evan Bird 飾）年紀輕輕卻因為毒而被關(guān)進了戒毒所女兒阿加莎（米婭·希科沃斯卡 Mia Wasikowska 飾）更糟，她竟然因呰鼠縱火而被關(guān)入了精病院。 不僅家庭活陷入了困境，桑福的事業(yè)亦走到了瓶頸哈瓦那（朱麗安·摩 Julianne Moore 飾）是桑福德的病人蟜亦是一演員，她生活在同為名演員的母親的陰影下，甚至連做夢也被親的幻影所糾纏。阿莎出院了，本杰亦回了家庭之中，孩子義均歸來帶給桑福德的是大的麻煩，和更混亂生活?
Eminent Boston Psychiatrist, Frasier Crane, last seen gracing the bars of Cheers has left his life there to start afresh in Seattle. He now has a spot as a popular radio Psychiatrist, giving him the chance to spread words of wit and wisdom to the masses. He shares his apartment with his retired cop father, Martin, and his father's physical care assistant, Daphne Moon. Add in brother Niles, Eddie the dog, some bizarre situations and plenty of humour and you've got all the ingredients for an excellent show and worthy successor to Cheers.
